1、建立涉及7200人的自然妊娠出生队列
完成7200余名研究对象及其子代的全孕期及产后长期随访工作，其中涵盖1200余名丈夫的孕期调查和样本采集。通过结构化问卷已获取生活方式和行为特征、疾病和用药史、孕产史、压力、抑郁和焦虑、环境暴露等信息，同时完成多时点体格测量和基本检查，并链接研究对象的诊疗信息。已累计收集调查问卷4万余份、生物样本8万余份，建立起丰富的数据库和生物样本库。队列目前针对子代在开展长期纵向随访工作。
2、建立重点专病流行病学研究
建立涉及1230人的妊娠期糖尿病巢式病例对照研究和1086人的不良妊娠结局病例队列研究。利用结构化问卷和多组学数据发现多种与妊娠期糖尿病显著相关的危险因素和生物标志物，如生活方式、遗传易感性、蛋白标志物、小分子代谢物、环境污染物、肠道菌群特征等，累计在Adv Sci、BMC Med、Am J Clin Nutr、Environ Sci Technol、Eur J Endocrinol、Clin Chem、J Clin Endocrinol Metab、Obesity、BJOG等权威期刊发表论文20余篇，并有多篇论文正在送审及准备中。
3、授权专利
构建妊娠期糖尿病的风险预测模型，以项目“妊娠期糖尿病的孕早期血液脂质生物标志物的筛选及应用”获授权专利一项（专利号：ZL 2021 1 0736608.0）。
4、获奖
项目“中国妊娠期糖尿病的营养影响因素研究“获第五届（2023年）妇幼健康科技奖-自然科学奖二等奖。项目“妊娠期糖尿病的孕早期预测和高危人群筛查技术“在“创青春”首届全国卫生健康行业青年创新大赛中获金奖。
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