基于天津妊娠期糖尿病队列，研究团队针对GDM患病率监测、危险因素及预测、生物标志物与基因位点等主要内容发表相关论文五十余篇，申请计算机软件专著1项，IDF邀请国际会议发言4次，国外医学转化指导1次。

[1] Jing Li, Xiaoxu Huo, Yun-Feng Cao, Sai-Nan Li, Zuo Du, Ping Shao, Junhong Leng, Cuiping Zhang, Xiao-Yu Sun, Ronald C W Ma, Zhong-Ze Fang, Xilin Yang*. Bile acid metabolites in early pregnancy and risk of gestational diabetes in Chinese women: A nested case-control study[J]. EBioMedicine, 2018, 35: 317-324.

[2] Jing Li, Jinnan Liu, Cuiping Zhang, Gongshu Liu, Junhong Leng, Leishen Wang, Weiqin Li, Zhijie Yu, Gang Hu, Juliana C.N. Chan, Xilin Yang*. Effects of lifestyle intervention of maternal gestational diabetes on offspring growth pattern before two years of age[J]. Diabetes Care, 2021,44:e42-e44.

[3] Weihan Cao, Ninghua Li, Rui Zhang, Weiqin Li, Ming Gao, Hui Wang, Leishen Wang, Yijuan Qiao, Jing Li, Zhijie Yu, Gang Hu, Junhong Leng, Xilin Yang*. Interactive effects of gestational diabetes and high pre‐pregnancy body mass index on adverse growth patterns of offspring[J]. Diabetes/Metabolism Research and Reviews, 2023: e3759.

[4] Ninghua Li, Junhong Leng, Rui Zhang, Hui Wang, Weiqin Li, Shuang Zhang , Yijuan Qiao, Jing Li, Zhijie Yu, Gang Hu, Zhongze Fang, Xilin Yang*. Maternal serum branched-chain amino acids in early pregnancy and offspring growth patterns from 1 year to 8 years of age[J]. Chinese Medical Journal, 2024: 10.1097.

[5] Xilin Yang*, Huiguang Tian, Fuxia Zhang, Cuiping Zhang, Yi Li, Junhong Leng, Leishen Wang, Gongshu Liu, Ling Dong, Zhijie Yu, Gang Hu, Juliana Cn Chan. A randomised translational trial of lifestyle intervention using a 3-tier shared care approach on pregnancy outcomes in Chinese women with gestational diabetes mellitus but without diabetes[J]. Journal of Translational Medicine, 2014, 12(1): 1-11.

[6] Junhong Leng, Ping Shao, Cuiping Zhang, Huiguang Tian, Fuxia Zhang, Shuang Zhang, Ling Dong, Lili Li, Zhijie Yu, Juliana C N Chan, Gang Hu, Xilin Yang*. Prevalence of gestational diabetes mellitus and its risk factors in Chinese pregnant women: a prospective population-based study in Tianjin, China[J]. PloS one, 2015, 10(3): e0121029.

[7] Lei Pan, Junhong Leng, Gongshu Liu, Cuiping Zhang, Huikun Liu, Min Li, Linglin Tan, Huiguang Tian, Juliana C N Chan, Gang Hu, Zhijie Yu, Xilin Yang*. Pregnancy outcomes of Chinese women with gestational diabetes mellitus defined by the IADPSG's but not by the 1999 WHO's criteria[J]. Clinical endocrinology, 2015, 83(5): 684-693.

[8] Jing Li, Peng Wang, Cuiping Zhang, Junhong Leng, Nan Li, Leishen Wang, Wei Li, Huikun Liu, Zhijie Yu, Gang Hu, Juliana C N Chan, Xilin Yang*. Short body height and pre-pregnancy overweight for increased risk of gestational diabetes mellitus: a population-based cohort study[J]. Frontiers in endocrinology, 2018, 9: 349.

[9] Ninghua Li#, Jing Li#, Hui Wang, Jinnan Liu, Weiqin Li, Kai Yang, Xiaoxu Huo, Junhong Leng, Zhijie Yu, Gang Hu, Zhongze Fang*, Xilin Yang*. Branched-chain amino acids and their interactions with lipid metabolites for increased risk of gestational diabetes. J Clin Endocrinol Metab, 2022,107(7):e3058-e3065. 

[10] Jinnan Liu#, Jing Li#, Sainan Li, Junhong Leng, Weiqin Li, Wen Yang, Xiaoxu Huo, Liwei Chen, Ronald C W Ma, Gang Hu, Zhongze Fang*, Xilin Yang*. Circulating Lysophosphatidylcholines in Early Pregnancy and Risk of Gestational Diabetes in Chinese Women. J Clin Endocrinol Metab, 2020, 105(4): e982-e993. 

[11] Xiaoxu Huo#, Jing Li#, Yun-Feng Cao, Sai-Nan Li, Ping Shao, Junhong Leng, Weiqin Li, Jinnan Liu, Kai Yang, Ronald CW Ma, Gang Hu, Zhongze Fang*, Xilin Yang*. Trimethylamine N-Oxide Metabolites in Early Pregnancy and Risk of Gestational Diabetes: A Nested Case-Control Study. J Clin Endocrinol Metab, 2019, 104(11):5529-5539. 

[12] Hongwei Liu#, Jing Li#, Junhong Leng, Hui Wang, Jinnan Liu, Weiqin Li, Hongyan Liu, Shuo Wang, Jun Ma, Juliana CN Chan, Zhijie Yu, Gang Hu, Changping Li*, Xilin Yang. Machine learning risk score for prediction of gestational diabetes in early pregnancy in Tianjin, China. Diabetes Metab Res Rev, 2021, 37(5):e3397. 

[13] Ming Gao, Jing Li, Rui Zhang, Ninghua Li, Weiqin Li, Shuang Zhang, Peng Wang, Hui Wang, Zhongze Fang, Zhijie Yu, Gang Hu, Junhong Leng, Xilin Yang*. Serum mannan-binding lectin-associated serine proteases in early pregnancy for gestational diabetes in Chinese pregnant women[J]. Frontiers in Endocrinology, 2023, 14: 1230244.

[14] Ming Gao#, Hui Wang#, Weiqin Li, Ping Shao, Ninghua Li, Jinnan Liu, Peng Wang, Shuang Zhang, Jing Li, Zhijie Yu, Gang Hu, Junhong Leng*, Xilin Yang*. Parental prepregnancy obesity and offspring overweight before two years of age among Chinese women with gestational diabetes. Prim Care Diabetes. 2023,17(1):85-90. 

[15] Ming Gao#, Hui Wang#, Weiqin Li, Leishen Wang, Ninghua Li, Yijuan Qiao, Tao Zhang, Jing Li, Zhijie Yu, Gang Hu, Junhong Leng*, Xilin Yang*. Maternal insulin resistance and maternal β-cell function during pregnancy for offspring overweight before 2 years of age among women with gestational diabetes. Pediatr Obes, 2023,18(3):e12995. 

[16] Hui Wang#, Jing Li#, Jinnan Liu, Junhong Leng, Weiqin Li, Zhijie Yu, Claudia H. T. Tam, Gang Hu, Ronald C. W. Ma, Zhongze Fang, Ying Wang*, Xilin Yang*. Interactions of CDKAL1 rs7747752 polymorphism and serum levels of L-carnitine and choline are related to increased risk of gestational diabetes mellitus. Genes Nutr, 2022,17(1):14. 

[17] Hui Wang#, Jing Li#, Junhong Leng, Weiqin Li, Jinnan Liu, Xiaoyan Yan, Zhijie Yu, Gang Hu, Ronald C. W. Ma, Zhongze Fang*, Ying Wang*, Xilin Yang*. The CDKAL1 rs7747752-Bile Acids Interaction Increased Risk of Gestational Diabetes Mellitus: A Nested Case-Control Study. Front Endocrinol (Lausanne), 2022,13:808956. 

[18] Jinnan Liu, Jing Li, Weiqin Li, Ninghua Li, Xiaoxu Huo, Hui Wang, Junhong Leng, Zhijie Yu, Ronald C W Ma, Gang Hu, Zhongze Fang*, Xilin Yang*. Predictive values of serum metabolites in early pregnancy and their possible pathways for gestational diabetes: A nested case-control study in Tianjin, China. J Diabetes Complications, 2021,35(12):108048. 

[19] Dingyu Cui#, Wen Yang#, Ping Shao, Jing Li, Peng Wang, Junhong Leng, Shuo Wang, Enqing Liu, Juliana C N Chan, Zhijie Yu, Gang Hu, Xilin Yang*. Interactions between Prepregnancy Overweight and Passive Smoking for Macrosomia and Large for Gestational Age in Chinese Pregnant Women. Obes Facts, 2021, 14(5):520-530. 

[20] Ninghua Li#, Jing Li#, Cuiping Zhang, Gongshu Liu, Junhong Leng, Jinnan Liu, Leishen Wang, Weiqin Li, Zhijie Yu, Gang Hu, Juliana C N Chan, Xilin Yang*. Usefulness of cut-off points of International criteria for prediction of post-partum diabetes and prediabetes among Chinese women with gestational diabetes. Diabetes Metab Res Rev, 2021, 37(8):e3456. 

[21] Qiulun Zhou#, Ying Wang#, Yuqin Gu, Jing Li, Hui Wang, Junhong Leng, Weiqin Li, Zhijie Yu, Gang Hu, Ronald Ching Wan Ma, Zhongze Fang*, Xilin Yang*, Guozhi Jiang*. Genetic variants associated with beta-cell function and insulin sensitivity potentially influence bile acid metabolites and gestational diabetes mellitus in a Chinese population. BMJ Open Diabetes Res Care, 2021, 9(1):e002287. 

[22] Wen Yang#, Jin Liu#, Jing Li, Jinnan Liu, Hongyan Liu, Yue Wang, Junhong Leng, Shuo Wang, Huaxi Chen, Juliana C.N. Chan, Zhijie Yu, Gang Hu, Xilin Yang*. Interactive effects of prepregnancy overweight and gestational diabetes on macrosomia and large for gestational age: A population-based prospective cohort in Tianjin, China. Diabetes Res Clin Pract, 2019, 154: 82-89. 

[23] 杨西林#,*,胡刚*. 天津妊娠期糖尿病预防项目：20年妊娠期糖尿病及并发症防治历程 [J]. 中华糖尿病杂志, 2022, 14(1): 12-16. 

[24] Shu Cao#, Ninghua Li#, Cuiping Zhang, Jinnan Liu, Hui Wang, Junhong Leng, Leishen Wang, Weiqin Li, Zhijie Yu, Gang Hu, Jing Li*, Xilin Yang*. Adverse pregnancy outcomes are associated with an increased risk of postpartum prediabetes and diabetes in Chinese women with gestational diabetes. Diabetes Res Clin Pract, 2022;186:109817.  

[25] 高铭#, 刘津楠, 冷俊宏, 李卫芹, 杨西林, 李婧*.妊娠早期胆汁酸代谢产物与超重之间的关联研究 [J]. 中华内分泌代谢杂志, 2021, 37(6): 523-528. 

软件著作权:

1.刘红伟,李长平,杨西林,李婧.妊娠糖尿病风险评估系统V1.0, 2020SR0218425, 原始取得, 全部权利, 2020-1-15